Searching for novel MDM2/MDMX dual inhibitors through a drug repurposing approach,Journal of Enzyme inhibition and Medicinal Chemistry

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Searching for novel MDM2/MDMX dual inhibitors through a drug repurposing approach
Journal of Enzyme inhibition and Medicinal Chemistry ( IF 5.6 ) Pub Date : 2023-12-07 , DOI: 10.1080/14756366.2023.2288810
Keting Li ₁ , Wenshu Hu ₁ , Yingjie Wang ₁ , Wenxing Chen ₁ , Hongmei Wen ₁ , Jian Liu ₁ , Wei Li ₁ , Bo Wang ₁

Affiliation

Disruption of p53-MDM2/MDMX interaction by smaller inhibitors is a promising therapeutic intervention gaining tremendous interest. However, no MDM2/MDMX inhibitors have been marketed so far. Drug r...

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