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Discovery of LAH-1 as potent c-Met inhibitor for the treatment of non-small cell lung cancer
Journal of Enzyme inhibition and Medicinal Chemistry ( IF 5.6 ) Pub Date : 2023-12-11 , DOI: 10.1080/14756366.2023.2286435
Lijie Sima 1 , Zhongyuan Wang 2 , Ling Yu 3 , Youli Hou 4 , Dongsheng Zhao 4 , Bilan Luo 4 , Weike Liao 4 , Xinfu Liu 1
Affiliation  

Dysregulated HGF/c-Met pathway has been implicated in multiple human cancers and has become an attractive target for cancer intervention. Herein, we report the discovery of N-(3-fluoro-4-((2-(3-hyd...

中文翻译:

发现 LAH-1 作为有效的 c-Met 抑制剂用于治疗非小细胞肺癌

失调的 HGF/c-Met 通路与多种人类癌症有关,并已成为癌症干预的一个有吸引力的目标。在此,我们报告了 N-(3-氟-4-((2-(3-hyd...
更新日期:2023-12-11
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