Abstract

People have become conscious about recycling or reusing many things they use in the 21st century because diminishing vital resources make it necessary, both personally and socially. The evaluation of waste is also critical in terms of national economies. In this study, starch dicarboxylic compounds were synthesized using waste potato peels (WPP) in the presence of sodium hypophosphite monohydrate as a catalyst for the formation of the ester cross-links. Adipic acid, succinic acid, and glutaric acid were employed with waste potato starch (WPS) to obtain cross-linked samples: WPS-A, WPS-S, and WPS-G, respectively. The obtained compounds were characterized by attenuated total reflectance Fourier transform infrared (FTIR-ATR), scanning electron microscopy with energy-dispersive X-ray analysis (SEM-EDX), X-ray diffraction (XRD), and their cytotoxicity properties were investigated. The biocompatibility of the obtained WPS-dicarboxylic acid compounds against NIH-3T3 and L929 murine fibroblast cells with MTT assay was determined. Studies have shown that these compounds do not harm healthy cells and are found to be bioavailable.

中文翻译：

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马铃薯皮废淀粉交联二元酸的合成、表征及生物相容性

摘要

人们已经开始意识到回收或再利用他们在 21 世纪使用的许多东西，因为重要资源的减少使得有必要这样做，无论是个人还是社会。废物评估对于国民经济也至关重要。在这项研究中，使用废马铃薯皮 (WPP) 在次磷酸钠一水合物作为酯交联形成催化剂的存在下合成淀粉二羧酸化合物。将己二酸、琥珀酸和戊二酸与废马铃薯淀粉（WPS）一起使用，分别获得交联样品：WPS-A、WPS-S和WPS-G。采用衰减全反射傅里叶变换红外(FTIR-ATR)、扫描电子显微镜-能量色散X射线分析(SEM-EDX)、X射线衍射(XRD)对所得化合物进行了表征，并研究了其细胞毒性特性。采用MTT法测定所得WPS-二羧酸化合物对NIH-3T3和L929小鼠成纤维细胞的生物相容性。研究表明，这些化合物不会损害健康细胞，并且具有生物利用度。