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Predictors of postoperative physical functional decline at hospital discharge in elderly patients with prolonged intensive care unit stay after cardiac surgery
Heart & Lung ( IF 2.8 ) Pub Date : 2023-12-08 , DOI: 10.1016/j.hrtlng.2023.11.014
Yosuke Honda , Keisuke Honma , Shuuji Nishimura , Shiomi Nakao , Naoki Sasanuma , Eri Manabe , Yuuki Uchiyama , Keiko Takahashi , Taichi Sakaguchi , Kazuhisa Domen

A prolonged stay in the intensive care (ICU) is associated with physical function decline following cardiac surgery. To predict physical function decline after cardiac surgery, it may be important to evaluate physical function in the ICU. This study aimed to determine that physical function examination at ICU discharge was independently associated with physical functional decline at hospital discharge in elderly patients who had undergone cardiac surgery and prolonged the ICU stay. We assessed physical function before and after cardiac surgery in elderly patients who had spent ≥72 h in the ICU in this retrospective cohort study using the short physical performance battery (SPPB). At hospital discharge, a decrease of at least 1 point on the SPPB was considered a postoperative physical functional decline. Postoperative physical functional decline at hospital discharge was predicted using multiple logistic regression. We revealed postoperative physical functional deterioration in 28.0% of patients who spent ≥72 h in the ICU following cardiac surgery. The Medical Research Council sum score (MRC-SS) (OR: 0.96, 95% CI: 0.82–0.99) and mechanical ventilation days (OR: 1.27, 95% CI: 1.01–1.64) were independently associated with physical functional decline at hospital discharge. Physical function at ICU discharge and mechanical ventilation days were predictors of postoperative physical functional decline at hospital discharge in patients. MRC-SS was more accurate in predicting postoperative physical functional decline at hospital discharge when performed at the time of ICU discharge.

中文翻译:

心脏手术后长期留在重症监护室的老年患者出院时身体功能下降的预测因素

长时间住在重症监护室 (ICU) 与心脏手术后身体功能下降有关。为了预测心脏手术后身体功能的下降,在 ICU 中评估身体功能可能很重要。本研究旨在确定接受心脏手术并延长 ICU 住院时间的老年患者出院时的身体功能检查与出院时身体功能下降的独立相关性。在这项回顾性队列研究中,我们使用短期身体表现电池(SPPB)评估了在 ICU 度过≥72小时的老年患者心脏手术前后的身体功能。出院时,SPPB 下降至少 1 分被认为是术后身体功能下降。使用多元逻辑回归预测术后出院时身体功能下降。我们发现,心脏手术后在 ICU 停留≥72 小时的患者中,28.0% 的患者术后身体功能恶化。医学研究委员会总分 (MRC-SS)(OR:0.96,95% CI:0.82–0.99)和机械通气天数(OR:1.27,95% CI:1.01–1.64)与医院身体功能下降独立相关释放。出ICU时的身体功能和机械通气天数是患者出院时术后身体功能下降的预测因素。在 ICU 出院时进行 MRC-SS 可以更准确地预测出院时术后身体功能下降。
更新日期:2023-12-08
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