Revascularization treatments (IV thrombolysis, mechanical thrombectomy) related to ischemic stroke have developed in recent years. With devices such as NIRS, non-invasive monitoring of treatment efficacy is provided. In this study, we aimed to use near-infrared spectroscopy (NIRS) as an objective monitoring method to see the effect of intravenous (IV) thrombolysis or mechanical thrombectomy treatments applied for cerebral oxygenation in patients with acute ischemic stroke. This study was carried out as a prospective study involving patients admitted to the emergency department in the years 2021–2022. NIRS measured regional oxygen saturation (rSO2) of both hemispheres of the brain before IV thrombolysis treatment, during the treatment at 0. min, 15. min, 30. min, 45. min, 60. min, after the treatment, and before and after the mechanical thrombectomy procedure. The significance level of the change in rSO2 values measured by NIRS was examined. 80 patients were included in the study. IV thrombolysis was applied to 58 patients, mechanical thrombectomy was applied to 5 of them, and both treatments were applied to 17 of them. In patients receiving IV thrombolysis, a significant difference was found in the affected hemisphere between the NIRS values measured at 0.min–15.min, 0.min–30.min, 0.min–45.min, 0.min–60.min, 0.min-post-treatment, 15.min-60.min (p < 0.001). In the patients included in the study, there was a strong and significant negative correlation between the deltaNIHSS value and the deltaNIRS values in the affected hemisphere (r=− 0.307, p = 0.013). There was a significant increase in the NIRS measurement values during and after the IV thrombolysis treatment in the affected hemisphere in the group with clinical improvement (p < 0.001). It is thought that IV thrombolysis or mechanical thrombectomy treatment applied to patients admitted to the emergency department with acute ischemic stroke can be followed objectively by NIRS.

近年来，与缺血性中风相关的血运重建治疗（静脉溶栓、机械血栓切除术）得到了发展。借助 NIRS 等设备，可以对治疗效果进行非侵入性监测。在本研究中，我们旨在使用近红外光谱（NIRS）作为客观监测方法，观察静脉（IV）溶栓或机械取栓治疗对急性缺血性卒中患者脑氧合的效果。这项研究是一项前瞻性研究，涉及 2021-2022 年急诊科收治的患者。NIRS测量静脉溶栓治疗前、治疗过程中0.min、15.min、30.min、45.min、60.min、治疗后、治疗前和治疗前和治疗后大脑两半球的局部氧饱和度（rSO2）机械取栓手术后。检查了 NIRS 测量的 rSO2 值变化的显着性水平。该研究纳入了 80 名患者。静脉溶栓58例，机械取栓5例，两种治疗17例。在接受静脉溶栓的患者中，在受影响的半球中，0.min-15.min、0.min-30.min、0.min-45.min、0.min-60 测量的 NIRS 值之间存在显着差异。 .min、治疗后 0.min、15.min-60.min (p < 0.001)。在研究纳入的患者中，受影响半球的 deltaNIHSS 值和 deltaNIRS 值之间存在强烈且显着的负相关性 (r=− 0.307，p = 0.013)。在临床改善组中，在静脉溶栓治疗期间和之后，受影响半球的 NIRS 测量值显着增加（p < 0.001）。人们认为，NIRS 可以客观地追踪急诊科收治的急性缺血性卒中患者的静脉溶栓或机械取栓治疗。