Haemorrhage during surgery is one of the major complications of hysterectomy, making it necessary to use haemostasis agents to reduce haemorrhage. The present study is designed to determine the effect of the oral drug Clonidine on reducing haemorrhage during hysterectomy surgery. A double-blind clinical trial was conducted on 70 candidates admitted for abdominal hysterectomy. Patients were selected using the convenient sampling method and were randomly divided into two A and B groups which received Clonidine (0.2 mg) and placebo tablets, respectively. The tablets were prescribed 90 min before entering the operating room. The haemorrhage during surgery was obtained by counting the number of surgical gauges, and the level of haemoglobin and haematocrit in both groups before and 6 and 12 h after the hysterectomy. The data were then analysed using descriptive statistics and interracial statistics. The results showed that the haemoglobin and haematocrit of the intervention group were significantly higher than that of the control group 12 h after the intervention. The average haemorrhage during surgery was 308.29 ± 58.99 in the intervention and 339.43 ± 56.10 in the control group, which is significantly higher in the control group as compared to the intervention group (P < 0.05). The overall findings of the current study indicate the effectiveness of oral administration of Clonidine for reducing haemorrhage during hysterectomy surgery without resulting in significant side effects.

手术过程中的出血是子宫切除术的主要并发症之一，因此需要使用止血剂来减少出血。本研究旨在确定口服药物可乐定对减少子宫切除手术期间出血的效果。对 70 名接受腹部子宫切除术的候选人进行了一项双盲临床试验。采用方便的抽样方法选择患者，并随机分为 A 组和 B 组，分别接受可乐定（0.2 mg）和安慰剂片剂。进入手术室前 90 分钟开药。术中出血量通过统计手术器械的数量以及子宫切除术前及术后6、12 h两组的血红蛋白和红细胞压积水平而获得。然后使用描述性统计和种族统计对数据进行分析。结果显示，干预后12 h，干预组的血红蛋白和红细胞压积显着高于对照组。术中平均出血量干预组为 308.29±58.99，对照组为 339.43±56.10，对照组显着高于干预组（P  < 0.05）。当前研究的总体结果表明，口服可乐定可有效减少子宫切除手术期间的出血，且不会产生明显的副作用。