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Effect of genetic polymorphisms on the pharmacokinetics of gefitinib in healthy Chinese volunteers
Xenobiotica ( IF 1.8 ) Pub Date : 2023-12-18 , DOI: 10.1080/00498254.2023.2294039 Ying-Rong Chen 1 , Xiang Yu 1 , Li-Min Xu 2 , Jue Mei 1 , Meng-Li Tian 1 , Min Xu 1 , Qiu-Yue Jin 1 , Li-Bing Ye 3 , Shui-Xin Yang 1
Xenobiotica ( IF 1.8 ) Pub Date : 2023-12-18 , DOI: 10.1080/00498254.2023.2294039 Ying-Rong Chen 1 , Xiang Yu 1 , Li-Min Xu 2 , Jue Mei 1 , Meng-Li Tian 1 , Min Xu 1 , Qiu-Yue Jin 1 , Li-Bing Ye 3 , Shui-Xin Yang 1
Affiliation
Gefitinib is the first-generation drug of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) metabolised by the cytochrome P450 and transported by P-glycoprotein (ABCB1) and br...
更新日期：2023-12-18
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