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[Retracted] miR‑141 inhibits prostatic cancer cell proliferation and migration, and induces cell apoptosis via targeting of RUNX1.
Oncology Reports ( IF 4.2 ) Pub Date : 2023-12-15 , DOI: 10.3892/or.2023.8679
Song Xu 1 , Jingping Ge 1 , Zhengyu Zhang 1 , Wenquan Zhou 1
Affiliation  

Following the publication of the above paper, a concerned reader drew to the Editor's attention that a number of plates showing colony formation assay data in Fig. 3A appeared to be overlapping, such that data purportedly showing the results from differently performed experiments may have been derived from the same original source(s); furthermore, certain of the cell‑cycle histograms shown in Fig. 4B were duplicated, again where they were intended to have shown results obtained under different experimental conditions. Subsequently, following an independent enquiry in the office, it was also noted that, in Fig. 2B, the data shown for the RUNX1 western blots were apparently the same for both the DU145 and PC‑2 cell lines. Although a corrigendum was requested by the authors, given the extent of the errors that were identified with respect to the compilation of as many as three of the figures in this paper, the Editor of Oncology Reports has decided that this article should be retracted from the publication owing to a lack of overall confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience that might result from the retraction of this article. [Oncology Reports 39: 1454‑1460, 2018; DOI: 10.3892/or.2018.6209].

中文翻译:


[撤回] miR-141 抑制前列腺癌细胞增殖和迁移,并通过靶向 RUNX1 诱导细胞凋亡。



上述论文发表后,一位关心的读者提请编辑注意,图 3A 中显示集落形成测定数据的许多板似乎重叠,因此可能得出了据称显示不同实验结果的数据。来自相同的原始来源;此外,图4B中显示的某些细胞周期直方图是重复的,同样是为了显示在不同实验条件下获得的结果。随后,在办公室进行独立调查后,还注意到,在图 2B 中,DU145 和 PC-2 细胞系的 RUNX1 蛋白质印迹显示的数据显然相同。尽管作者要求进行更正,但鉴于在本文中多达三张图表的编制中发现的错误程度,《肿瘤学报告》的编辑已决定从《肿瘤学报告》中撤回这篇文章。由于对所提供的数据缺乏总体信心而发表。作者被要求对这些担忧做出解释,但编辑部没有收到答复。对于因撤回本文而给读者带来的任何不便,编辑深表歉意。 [肿瘤学报告 39:1454-1460,2018 年; DOI:10.3892/或.2018.6209]。
更新日期:2023-12-15
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