The following outlines ethical reasons for widening the Human Genome Organisation’s (HUGO) mandate to include ecological genomics. The environment influences an organism’s genome through ambient factors in the biosphere (e.g. climate and UV radiation), as well as the agents it comes into contact with, i.e. the epigenetic and mutagenic effects of inanimate chemicals and pollution, and pathogenic organisms. Emerging scientific consensus is that social determinants of health, environmental conditions and genetic factors work together to influence the risk of many complex illnesses. That paradigm can also explain the environmental and ecological determinants of health as factors that underlie the (un)healthy ecosystems on which communities rely. We suggest that The Ecological Genome Project is an aspirational opportunity to explore connections between the human genome and nature. We propose consolidating a view of Ecogenomics to provide a blueprint to respond to the environmental challenges that societies face. This can only be achieved by interdisciplinary engagement between genomics and the broad field of ecology and related practice of conservation. In this respect, the One Health approach is a model for environmental orientated work. The idea of Ecogenomics—a term that has been used to relate to a scientific field of ecological genomics—becomes the conceptual study of genomes within the social and natural environment. The HUGO Committee on Ethics, Law and Society (CELS) recommends that an interdisciplinary One Health approach should be adopted in genomic sciences to promote ethical environmentalism. This perspective has been reviewed and endorsed by the HUGO CELS and the HUGO Executive Board.

中文翻译：

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人类基因组组织 (HUGO) 和生态基因组学的愿景：生态基因组计划

以下概述了扩大人类基因组组织 (HUGO) 职责范围以纳入生态基因组学的伦理原因。环境通过生物圈中的环境因素（例如气候和紫外线辐射）以及它所接触的物质（即无生命化学品和污染以及病原生物的表观遗传和诱变效应）影响生物体的基因组。新兴的科学共识是，健康的社会决定因素、环境条件和遗传因素共同影响许多复杂疾病的风险。该范式还可以将健康的环境和生态决定因素解释为社区所依赖的（不）健康生态系统的基础因素。我们认为生态基因组计划是探索人类基因组与自然之间联系的一个理想机会。我们建议整合生态基因组学的观点，为应对社会面临的环境挑战提供蓝图。这只能通过基因组学和广泛的生态学领域以及相关保护实践之间的跨学科合作来实现。在这方面，“同一个健康”方法是环境导向工作的典范。生态基因组学的概念——一个与生态基因组学科学领域相关的术语——成为社会和自然环境中基因组的概念研究。 HUGO 伦理、法律和社会委员会 (CELS) 建议在基因组科学中采用跨学科的“同一个健康”方法，以促进伦理环保主义。这一观点已得到 HUGO CELS 和 HUGO 执行委员会的审查和认可。