Stress exposure contributes to the onset, maintenance, and recurrence of major depressive disorder (MDD) in adolescents. However, the precise stress facets (e.g. chronicity, domain) most strongly linked to outcomes at different stages along the depression severity continuum remain unclear. Across two studies, chronic and episodic stressors were comprehensively assessed among: (a) healthy youth with (High-Risk [HR]) and without (Low-Risk [LR]) a maternal history of MDD and (b) adolescents with current MDD and suicide ideation and healthy controls (HC).

中文翻译：

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高危、抑郁和自杀青少年的压力暴露

压力暴露会导致青少年重度抑郁症 (MDD) 的发生、维持和复发。然而，与抑郁症严重程度连续体不同阶段的结果最密切相关的精确压力方面（例如长期性、领域）仍不清楚。在两项研究中，对以下人群的慢性和偶发性压力源进行了全面评估：(a) 有（高风险 [HR]）和无（低风险 [LR]）母亲 MDD 病史的健康青年，以及 (b) 目前患有 MDD 的青少年以及自杀意念和健康控制（HC）。