In this article, I put forward the idea that the neoplastic process (NP) has deep evolutionary roots and makes specific predictions about the connection between cancer and the formation of the first embryo, which allowed for the evolutionary radiation of metazoans. My main hypothesis is that NP is at the heart of cellular mechanisms responsible for animal morphogenesis and, given its embryological basis, also at the center of animal evolution. It is thus understood that NP-associated mechanisms are deeply rooted in evolutionary history and tied to the formation of the first animal embryo. In my consideration of these arguments, I expound on how cancer biology is perfectly intertwined with evolutionary biology. Finally, I describe essential cellular components of unicellular holozoans that served as a basis for the formation of the neoplastic functional module (NFM) and its subsequent exaptation, which brought forth two great biophysical revolutions within the first embryo.

在这篇文章中，我提出了肿瘤过程（NP）具有深厚的进化根源的观点，并对癌症与第一个胚胎形成之间的联系做出了具体的预测，这使得后生动物的进化辐射成为可能。我的主要假设是，NP 是负责动物形态发生的细胞机制的核心，并且鉴于其胚胎学基础，它也是动物进化的中心。由此可见，NP 相关机制深深植根于进化史，并与第一个动物胚胎的形成有关。在考虑这些论点时，我阐述了癌症生物学如何与进化生物学完美地交织在一起。最后，我描述了单细胞全动物的重要细胞成分，它们是肿瘤功能模块（NFM）形成及其随后的适应的基础，这在第一个胚胎中带来了两次伟大的生物物理革命。