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Increased SARS-CoV-2 reactive low avidity T cells producing inflammatory cytokines in pediatric post-acute COVID-19 sequelae (PASC)
Pediatric Allergy and Immunology ( IF 4.4 ) Pub Date : 2023-12-17 , DOI: 10.1111/pai.14060
Krystallenia Paniskaki 1, 2 , Sarah Goretzki 1, 3 , Moritz Anft 2 , Margarethe J. Konik 1 , Toni L. Meister 4 , Stephanie Pfaender 4 , Klara Lechtenberg 3 , Melanie Vogl 5 , Burcin Dogan 3 , Sebastian Dolff 1 , Timm H. Westhoff 6 , Hana Rohn 1 , Ursula Felderhoff‐Mueser 3, 7 , Ulrik Stervbo 2 , Oliver Witzke 1 , Christian Dohna‐Schwake 1, 3, 7 , Nina Babel 2, 8
Affiliation  

A proportion of the convalescent SARS-CoV-2 pediatric population presents nonspecific symptoms, mental health problems, and a reduction in quality of life similar to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID-19 symptomatic. However, data regarding its clinical manifestation and immune mechanisms are currently scarce.

中文翻译:

在儿科急性后 COVID-19 后遗症 (PASC) 中,产生炎症细胞因子的 SARS-CoV-2 反应性低亲和力 T 细胞增加

部分恢复期 SARS-CoV-2 儿科人群出现非特异性症状、心理健康问题以及生活质量下降,类似于肌痛性脑脊髓炎/慢性疲劳综合征 (ME/CFS) 和长期的 COVID-19 症状。然而,目前有关其临床表现和免疫机制的数据很少。
更新日期:2023-12-21
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