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Highly responsive diabetes and asthma sensors with WO3 nanoneedle films for the detection of biogases with low concentrations
NPG Asia Materials ( IF 9.7 ) Pub Date : 2023-12-22 , DOI: 10.1038/s41427-023-00515-7
Yoshitake Masuda , Ayako Uozumi

A diabetes sensor was developed to detect low concentrations of acetone gas, which is a diabetes biomarker. A WO3 nanoneedle film was synthesized via an aqueous process for use as a sensitive sensing membrane. Acetone was adsorbed and oxidized on the WO3 nanoneedle film, which changed the sensor resistance. The sensor exhibited a high response of Ra/Rg = 19.72, where Ra is the sensor resistance in air, and Rg is the sensor resistance in air containing 10 ppmv acetone gas. The sensor also exhibited a high response (25.36) to 1 ppmv NO2, which is related to asthma. Furthermore, the sensor responded to various biogases associated with diseases. The sensor responses to 10 ppmv of the lung cancer marker gases acetaldehyde and toluene were 13.54 and 9.49, respectively. The sensor responses to 10 ppmv isoprene, ethanol, para-xylene, hydrogen, and NH3 were 7.93, 6.33, 4.51, 2.08, and 0.90, respectively. Trace amounts of acetone and NO2 gases (25 and 250 ppbv, respectively) were detected. The limits of detection for acetone and NO2 gases were estimated to be 2.4 and 1.5 ppbv, respectively. The sensor exhibited superior ability to detect low concentrations of biomarker gases. The unique characteristics of the WO3 nanoneedle film contributed to its high response rates.



中文翻译:

具有 WO3 纳米针膜的高响应糖尿病和哮喘传感器,用于检测低浓度沼气

开发了一种糖尿病传感器来检测低浓度的丙酮气体,这是一种糖尿病生物标志物。通过水法合成了WO 3纳米针膜,用作敏感传感膜。丙酮在WO 3纳米针薄膜上被吸附和氧化,改变了传感器的电阻。该传感器表现出Ra / R g =  19.72的高响应,其中Ra是空气的传感器电阻,Rg是含有10 ppmv丙酮气体的空气中的传感器电阻。该传感器还对与哮喘相关的1 ppmv NO 2表现出高响应 (25.36) 。此外,传感器对与疾病相关的各种沼气做出反应。传感器对 10 ppmv 肺癌标记气体乙醛和甲苯的响应分别为 13.54 和 9.49。传感器对10 ppmv异戊二烯、乙醇、对二甲苯、氢气和NH 3的响应分别为7.93、6.33、4.51、2.08和0.90。检测到痕量丙酮和NO 2气体(分别为25 和250 ppbv)。丙酮和 NO 2气体的检测限估计分别为 2.4 和 1.5 ppbv。该传感器表现出检测低浓度生物标记气体的卓越能力。WO 3纳米针薄膜的独特特性有助于其高响应率。

更新日期:2023-12-22
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