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Serum thrombospondin-2 level changes with liver stiffness improvement in patients with type 2 diabetes
Clinical Endocrinology ( IF 3.2 ) Pub Date : 2023-12-21 , DOI: 10.1111/cen.15010
Jimmy Ho Cheung Mak 1 , David Tak‐Wai Lui 1 , Carol Ho‐Yi Fong 1 , Chloe Yu‐Yan Cheung 1 , Ying Wong 1 , Alan Chun‐Hong Lee 1 , Ruby Lai‐Chong Hoo 1, 2 , Aimin Xu 1, 2 , Kathryn Choon‐Beng Tan 1 , Karen Siu‐Ling Lam 1, 2 , Chi‐Ho Lee 1, 2
Affiliation  

Baseline circulating thrombospondin-2 (TSP2) level was identified as a potential novel hepatic fibrosis biomarker that associates with development and progression of hepatic fibrosis in patients with nonalcoholic fatty liver disease and type 2 diabetes. Here, we investigated whether circulating TSP2 levels changed with improvement in liver stiffness (LS), which reflects liver fibrosis on transient elastography.

中文翻译:

2型糖尿病患者血清血小板反应蛋白-2水平随肝硬度改善的变化

基线循环血小板反应蛋白-2 (TSP2) 水平被确定为一种潜在的新型肝纤维化生物标志物,与非酒精性脂肪肝病和 2 型糖尿病患者肝纤维化的发生和进展相关。在这里,我们研究了循环 TSP2 水平是否随着肝脏硬度 (LS) 的改善而变化,肝脏硬度 (LS) 反映了瞬时弹性成像上的肝纤维化。
更新日期:2023-12-21
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