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The Possible Role of the Superior Sagittal Sinus in Regulating Cerebrospinal Fluid Dynamics among Preterm Infants: A Case Report and a Review of the Literature
Neuropediatrics ( IF 1.4 ) Pub Date : 2023-12-23 , DOI: 10.1055/a-2202-3774
Chiara Andreato , Sara Uccella 1 , Marcella Battaglini , Mattia Pacetti , Domenico Tortora 2 , Luca Antonio Ramenghi
Affiliation  

We report the case of a preterm of 27 weeks of gestation who developed posthemorrhagic ventricular dilatation associated to a complete thrombosis of the superior sagittal sinus, for its peculiar interest in clarifying the physiology of the cerebrospinal fluid (CSF) dynamics.The exact CSF volume that must be removed to improve cerebral hemodynamics and outcomes in infants with posthemorrhagic ventricular dilatation is unknown. According to Volpe's studies, a volume of 10 to 15 mL/kg/die of body weight is commonly chosen. The subject we report needed an excessive CSF drainage (up to 32 mL/kg/d), in presence of a functioning external ventricular drain.We review the literature on the topic, and we postulate that the superior sagittal sinus may play an active role in the CSF dynamics of the immature brain (as it happens for the adult brain).

中文翻译:

上矢状窦在调节早产儿脑脊液动力学中的可能作用:病例报告和文献综述

我们报告一例妊娠 27 周的早产儿,其出现与上矢状窦完全血栓形成相关的出血后脑室扩张,因为该病例对阐明脑脊液 (CSF) 动力学的生理学特别感兴趣。必须去除以改善脑血流动力学,而出血后脑室扩张的婴儿的结局尚不清楚。根据 Volpe 的研究,通常选择 10 至 15 mL/kg/体重的体积。我们报告的受试者在脑室外引流功能正常的情况下需要过量的脑脊液引流(高达 32 mL/kg/d)。我们回顾了有关该主题的文献,并假设上矢状窦可能发挥积极作用未成熟大脑的脑脊液动力学(就像成人大脑一样)。
更新日期:2023-12-24
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