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Serial electrocardiograms at follow-up for early detection of transplanted heart rejection: A viewpoint
Journal of Electrocardiology ( IF 1.3 ) Pub Date : 2023-12-20 , DOI: 10.1016/j.jelectrocard.2023.12.008
John E. Madias

This viewpoint proposed that serial electrocardiograms (ECG) could be used to monitor for heart transplantation (HT) rejection, based on the expected attenuation of the amplitude of ECG QRS complexes (attQRS) engendered by the rejection-induced decrease in electrical resistance due to the underlying myocardial edema (ME). Previous work in humans has shown attQRS in the setting of a diverse array of edematous states, affecting the myocardium (i.e, ME) and the body volume conductor “enveloping” the heart. Also, animal and human experience has revealed low electrical resistance during mild/moderate HT rejection. Studies with serial correlations of endomyocardial biopsy (EMB), echocardiography, cardiac magnetic resonance imaging, and ECG are recommended, which will merely require recording of an ECG, when EMB and imaging studies are carried out for monitoring of post-HT rejection.



中文翻译:

早期发现移植心脏排斥反应的随访时连续心电图:一个观点

这种观点提出,连续心电图 (ECG) 可用于监测心脏移植(HT) 排斥反应,这是基于预期的心电图 QRS 波群 (attQRS) 振幅衰减,该衰减是由排斥引起的电阻下降引起的。潜在的心肌水肿(ME)。先前对人类的研究表明,attQRS 在多种水肿状态下会影响心肌(即 ME)和“包围”心脏的身体容量导体。此外,动物和人类的经验表明,在轻度/中度 HT 排斥过程中电阻较低。建议进行心内膜心肌活检(EMB)、超声心动图、心脏磁共振成像和心电图的系列相关研究,当进行 EMB 和影像学研究以监测 HT 后排斥反应时,仅需要记录心电图。

更新日期:2023-12-25
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