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Hepatitis C virus cure from direct-acting antivirals and mortality: Are people with and without a history of injection drug use in the same boat? (ANRS CO22 Hepather cohort)
Drug and Alcohol Review ( IF 4.042 ) Pub Date : 2023-12-22 , DOI: 10.1111/dar.13802 Tangui Barré 1 , Marc Bourlière 1, 2 , Lucia Parlati 3 , Clémence Ramier 1 , Fabienne Marcellin 1 , Camelia Protopopescu 1 , Vincent Di Beo 1 , Carole Cagnot 4 , Celine Dorival 5 , Jérôme Nicol 5 , Fabien Zoulim 6, 7, 8 , Fabrice Carrat 9 , Patrizia Carrieri 1 ,
Drug and Alcohol Review ( IF 4.042 ) Pub Date : 2023-12-22 , DOI: 10.1111/dar.13802 Tangui Barré 1 , Marc Bourlière 1, 2 , Lucia Parlati 3 , Clémence Ramier 1 , Fabienne Marcellin 1 , Camelia Protopopescu 1 , Vincent Di Beo 1 , Carole Cagnot 4 , Celine Dorival 5 , Jérôme Nicol 5 , Fabien Zoulim 6, 7, 8 , Fabrice Carrat 9 , Patrizia Carrieri 1 ,
Affiliation
The risk of mortality in people with a history of injection drug use (PHID) is high, as is the prevalence of hepatitis C virus (HCV) infection. Although direct-acting antivirals (DAA) are effective in this population in terms of sustained virological response, it is not known whether PHID benefit as much as people with no history of injection drug use from DAA-related HCV cure in terms of reduced all-cause mortality.
中文翻译：
直接作用抗病毒药物治愈丙型肝炎病毒和死亡率：有和没有注射吸毒史的人是否在同一条船上？（ANRS CO22 Hepather 队列）
有注射吸毒 (PHID) 史的人的死亡风险很高，丙型肝炎病毒 (HCV) 感染的患病率也很高。尽管直接作用抗病毒药物 (DAA) 在持续病毒学反应方面对该人群有效，但尚不清楚 PHID 是否能像无注射吸毒史的人一样从 DAA 相关的 HCV 治愈中获益，从而减少总体感染。导致死亡。
更新日期：2023-12-22
中文翻译：
直接作用抗病毒药物治愈丙型肝炎病毒和死亡率：有和没有注射吸毒史的人是否在同一条船上？（ANRS CO22 Hepather 队列）
有注射吸毒 (PHID) 史的人的死亡风险很高，丙型肝炎病毒 (HCV) 感染的患病率也很高。尽管直接作用抗病毒药物 (DAA) 在持续病毒学反应方面对该人群有效，但尚不清楚 PHID 是否能像无注射吸毒史的人一样从 DAA 相关的 HCV 治愈中获益，从而减少总体感染。导致死亡。
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