Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by recurrent episodes of pain. This study aimed to describe the temporal daily relationships between sleep and pain in adolescents with SLE. Twenty-three adolescents with SLE recruited from a pediatric hospital wore actigraphy and completed diaries. Generalized estimating equation models were used. On average, evening pain negatively predicted subsequent sleep quality that night, and, on average, sleep quality negatively predicted morning pain. Shorter total sleep time significantly predicted higher morning pain (95% confidence intervals [CI], −0.38 to −0.03, p = .02), whereas sleep efficiency and sleep quality were not significantly associated with morning pain (95% CI, −0.03 to 0.03; 95% CI, −0.08 to 0.06, respectively). Subsequent evening pain did not predict daily nighttime sleep Our findings suggest that sleep is a target for pain interventions to include among adolescents with SLE.

中文翻译：

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系统性红斑狼疮青少年睡眠与疼痛之间的日常时间关系

系统性红斑狼疮（SLE）是一种慢性自身免疫性疾病，其特征是反复发作的疼痛。本研究旨在描述患有系统性红斑狼疮的青少年的睡眠和疼痛之间的日常时间关系。从儿科医院招募的 23 名患有系统性红斑狼疮的青少年佩戴了体动记录仪并填写了日记。使用广义估计方程模型。平均而言，晚上的疼痛对当晚随后的睡眠质量有负面影响，而平均而言，睡眠质量对早晨的疼痛有负面影响。较短的总睡眠时间显着预测较高的早晨疼痛（95% 置信区间 [CI]，-0.38 至 -0.03，p = .02），而睡眠效率和睡眠质量与早晨疼痛没有显着相关性（95% CI，-0.03）至 0.03；95% CI，分别为 -0.08 至 0.06）。随后的夜间疼痛并不能预测每日夜间睡眠。我们的研究结果表明，睡眠是 SLE 青少年疼痛干预的目标。