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Cerebellar roots of aggression in violent psychopathic offenders: evidence from structural neuroimaging studies
Current Opinion in Behavioral Sciences ( IF 5 ) Pub Date : 2023-12-26 , DOI: 10.1016/j.cobeha.2023.101333
Jana Klaus , Elze ML Wolfs , Dennis JLG Schutter

Investigations of structural brain abnormalities in antisocial personality disorder and psychopathy associated with aggression have focused on prefrontal, limbic, and paralimbic regions. In this narrative review, a series of structural neuroanatomical studies are discussed, which points toward an important role of the cerebellum in antisocial and aggressive behavior. Across the reviewed studies, volumetric reduction of the vermis and right posterior cerebellum was a consistent finding in violent psychopathic offenders. The observations agree with results in healthy volunteers, which show that volumes of the vermis and right cerebellar hemisphere are correlated with impulsivity and aggressive behavior. Deviations in cerebellar volumes in violent psychopathic offenders are proposed to be part of a deficient neural circuit implicated in emotion regulation and executive functions.



中文翻译:

暴力精神病罪犯的攻击行为的小脑根源:来自结构神经影像学研究的证据

对反社会人格障碍和与攻击性相关的精神病的大脑结构异常的研究主要集中在前额叶、边缘和旁边缘区域。在这篇叙述性评论中,讨论了一系列结构神经解剖学研究,这些研究指出小脑在反社会和攻击行为中的重要作用。在所有审查的研究中,在暴力精神病罪犯中一致发现蚓部和右后小脑的体积减少。这些观察结果与健康志愿者的结果一致,表明蚓部和右小脑半球的体积与冲动和攻击行为相关。暴力精神病罪犯的小脑体积偏差被认为是与情绪调节和执行功能有关的神经回路缺陷的一部分。

更新日期:2023-12-27
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