The hypothyroid phenotype associated with resistance to thyroid hormone alpha (RTH-α) is associated with a diverse clinical picture. On the other hand, thyroid-stimulating hormone (TSH) levels are normal. Free triiodothyronine (fT3) and free thyroxine (fT4) levels can also be normal; however, normo- or macrocytic anaemia is usually present in reported cases. Diagnosis is challenging and there is limited data regarding screening methods.

中文翻译：

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基于贫血的儿童甲状腺激素α抵抗筛查

与甲状腺激素α（RTH-α）抵抗相关的甲状腺功能减退表型与多种临床表现相关。另一方面，促甲状腺激素（TSH）水平正常。游离三碘甲状腺原氨酸 (fT3) 和游离甲状腺素 (fT4) 水平也可能正常；然而，在报告的病例中通常存在正常细胞性贫血或大细胞性贫血。诊断具有挑战性，并且有关筛查方法的数据有限。