Bariatric surgery results in rapid recovery of glucose control in subjects with type 2 diabetes mellitus. However, the underlying mechanisms are still largely unknown. The present study aims to clarify how bariatric surgery modifies pancreatic cell subgroup differentiation and transformation in the single-cell RNA level.

中文翻译：

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Zucker 糖尿病大鼠的单细胞转录组学表明，减肥手术可诱导胰腺细胞转分化

减肥手术可使 2 型糖尿病患者的血糖控制快速恢复。然而，其基本机制仍然很大程度上未知。本研究旨在阐明减肥手术如何在单细胞 RNA 水平上改变胰腺细胞亚群的分化和转化。