Exposure to adversity early in life (ELA) has been associated with elevated risk for depression during adolescence, particularly for females; the mechanisms underlying this association, however, are poorly understood. One potential mechanism linking ELA and sex differences in depressive symptoms is sleep disturbances, which increase during adolescence and are more common in females. Here, we examined whether sleep disturbances mediate the association between ELA and increases in depressive symptoms during adolescence and whether this mediation differs by sex.

中文翻译：

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青春期女性和男性早期生活逆境、睡眠障碍和抑郁症状之间的关联：一项纵向调查

早年经历逆境（ELA）与青春期抑郁症风险升高有关，尤其是对于女性而言；然而，人们对这种关联背后的机制知之甚少。将 ELA 与抑郁症状性别差异联系起来的一种潜在机制是睡眠障碍，这种情况在青春期会增加，并且在女性中更为常见。在这里，我们研究了睡眠障碍是否介导 ELA 与青春期抑郁症状增加之间的关联，以及这种介导是否因性别而异。