The objective of the study was to describe the patterns of antihypertensive medicines (AHM) in a selected national population in Ghana. The claims data for all privately insured patients in Ghana over three years to 2018 were analysed. The classes of medicines used, the dose by time, gender and age, and generic status were examined. In addition, the use in Defined Daily Dose (DDD) per 1000 population per day was estimated. Classes of AHM prescribed were CCB, ARB, ACEI, diuretics, and BB. Amlodipine, nifedipine, losartan, lisinopril, and bendroflumethiazide accounted for 74% of all use. The most widely used single CCB was amlodipine 3.92 DDD/1,000 population/day in 2016, 3.92 DDD/1,000 population/day in 2017, and 4.92 DDD/1,000 population/day in 2018. In those aged 51–60 years, use of CCB in women (74.0 DDD/1,000 population/day) was almost twice that of men (38.3 DDD/1,000 population/day). The top ten medicines accounted for 93% of all single medicine products in 2018. Most single medicine products was generic (76.5% in 2016; 79.9% in 2017 and 83.1% in 2018) whiles most fixed combination products were branded (73.0% in 2016; 89.7% in 2017 and 91.3% in 2018). The patterns of AHM use are clinically expected although the Ghana Standard Treatment guidelines are not directive about lines of treatment.

该研究的目的是描述加纳选定国民人群的抗高血压药物 (AHM) 模式。分析了截至 2018 年三年内加纳所有私人保险患者的索赔数据。检查了所用药物的类别、不同时间的剂量、性别和年龄以及一般状况。此外，还估计了每 1000 人每天的每日限定剂量 (DDD) 的使用量。处方的 AHM 类别包括 CCB、ARB、ACEI、利尿剂和 BB。氨氯地平、硝苯地平、氯沙坦、赖诺普利和苯氟噻嗪占全部使用量的 74%。最广泛使用的单一 CCB 是氨氯地平，2016 年为 3.92 DDD/1,000 人/天，2017 年为 3.92 DDD/1,000 人/天，2018 年为 4.92 DDD/1,000 人/天。在 51-60 岁的人群中，CCB 的使用女性（74.0 DDD/1,000 人/天）几乎是男性（38.3 DDD/1,000 人/天）的两倍。2018年，前十大药品占所有单药产品的93%。大多数单药产品是仿制药（2016年为76.5%；2017年为79.9%；2018年为83.1%），而大多数固定组合产品为品牌产品（2016年为73.0%） ；2017 年为 89.7%，2018 年为 91.3%）。尽管加纳标准治疗指南没有关于治疗方案的指导，但 AHM 的使用模式是临床预期的。