How chromatin configuration impacts DNA repair is an emerging question. A recent study by shows that ATM orchestrates a new chromatin compartment (D compartment) following DNA double-strand breaks and establishes that this compartment enhances cellular response to such breaks but also introduces a risk to genome integrity.

中文翻译：

---

DNA 损伤反应中的 ATM D 区室化

染色质结构如何影响 DNA 修复是一个新出现的问题。最近的一项研究表明，ATM 在 DNA 双链断裂后精心策划了一个新的染色质区室（D 区室），并确定该区室增强了细胞对此类断裂的反应，但也给基因组完整性带来了风险。