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A novel simple disposition index (SPINA-DI) from fasting insulin and glucose concentration as a robust measure of carbohydrate homeostasis
Journal of Diabetes ( IF 4.5 ) Pub Date : 2024-01-02 , DOI: 10.1111/1753-0407.13525
Johannes W. Dietrich 1, 2, 3, 4 , Assjana Abood 1, 2, 3, 4 , Riddhi Dasgupta 5 , Shajith Anoop 5 , Felix K. Jebasingh 5 , R. Spurgeon 6 , Nihal Thomas 5 , Bernhard O. Boehm 7, 8
Affiliation  

The widely used dynamic disposition index, derived from oral glucose tolerance testing, is an integrative measure of the homeostatic performance of the insulin-glucose feedback control. Its collection is, however, time consuming and expensive. We, therefore, pursued the question if such a measure can be calculated at baseline/fasting conditions using plasma concentrations of insulin and glucose.

中文翻译:

一种基于空腹胰岛素和葡萄糖浓度的新型简单处置指数 (SPINA-DI),作为碳水化合物稳态的有力衡量指标

广泛使用的动态处置指数源自口服葡萄糖耐量测试,是胰岛素-葡萄糖反馈控制的稳态性能的综合测量。然而,它的收集既耗时又昂贵。因此,我们探讨了是否可以使用胰岛素和葡萄糖的血浆浓度在基线/禁食条件下计算这样的测量值的问题。
更新日期:2024-01-04
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