The developing human cerebellum has a greater diversity of progenitor types than that of the mouse, necessitating a human-based model for studying cerebellar development and disease. Atamian et al.¹ developed a 3D organoid model of cerebellar development, which recapitulates many cell types found in the developing human cerebellum, including Purkinje-neuron-like cells.

中文翻译：

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改善人类小脑类器官的细胞多样性

正在发育的人类小脑的祖细胞类型比小鼠的小脑更加多样化，因此需要一个基于人类的模型来研究小脑发育和疾病。阿塔米安等人。¹开发了小脑发育的 3D 类器官模型，该模型概括了发育中的人类小脑中发现的许多细胞类型，包括浦肯野神经元样细胞。