Background. Acetabular fracture surgeries are frequently accompanied by protracted and severe perioperative pain, and there is no consensus on optimal pain relief management. Aim. This study aimed at comparing the analgesic efficacy of fascia iliaca compartment block (FICB) and quadratus lumborum block (QLB) in patients with acetabular fractures undergoing surgery using the Stoppa method. Methods. In this double-blind, randomized, noninferiority clinical trial, adult patients undergoing spinal anesthesia for acetabular fracture surgery, in Imam Hossein Hospital, Tehran, Iran (IRCT20191114045435N1), were randomly divided into two groups: FICB (n = 22) and QLB (n = 24). The visual analog scale (VAS) was used to assess the pain intensity at different times for all participants. In addition, the dose of fentanyl required to induce the patient to sit for spinal anesthesia and the pain intensity were evaluated. Moreover, the duration of analgesia and the total amount of morphine consumed in the first 24 h following surgery were evaluated, analyzed, and compared between the two study groups. Results. FICB and QLB demonstrated effective comparative postoperative analgesic profiles following acetabular fracture surgery; however, no significant differences in VAS values were observed between the two groups during the study. FICB experienced reduced cumulative fentanyl consumption during spinal anesthetic placement, whereas QLB had a significantly lower total morphine demand in the initial postoperative 24 h period. Conclusion. The lateral QLB and FICB can be introduced as effective routes for analgesia in acetabular fracture surgery using the Stoppa method. Clinical Trial Registration. The study was prospectively registered in the clinical trials registry system, on 2021-02-17, with registration number: IRCT20191114045435N1.

中文翻译：

---

Stoppa 法髋臼骨折手术中腰方肌阻滞与髂筋膜室阻滞的比较：双盲、随机、非劣效性试验

背景。髋臼骨折手术经常伴随着持久且严重的围手术期疼痛，并且对于最佳的疼痛缓解管理尚未达成共识。目的。本研究旨在比较髂筋膜间隙阻滞（FICB）和腰方肌阻滞（QLB）对采用 Stoppa 方法接受手术的髋臼骨折患者的镇痛效果。方法。在这项双盲、随机、非劣效性临床试验中，在伊朗德黑兰伊玛目侯赛因医院 (IRCT20191114045435N1) 接受脊髓麻醉进行髋臼骨折手术的成年患者被随机分为两组：FICB ( n  = 22) 和 QLB ( n  = 24)。使用视觉模拟量表（VAS）评估所有参与者在不同时间的疼痛强度。此外，还评估了诱导患者坐位进行脊髓麻醉所需的芬太尼剂量和疼痛强度。此外，对两个研究组之间的镇痛持续时间和术后24小时内消耗的吗啡总量进行评估、分析和比较。结果。FICB 和 QLB 证明了髋臼骨折手术后有效的术后镇痛效果对比；然而，在研究期间两组之间的 VAS 值没有观察到显着差异。FICB 在脊髓麻醉期间累积的芬太尼消耗量减少，而 QLB 在术后最初 24 小时内的吗啡总需求量显着降低。结论。外侧QLB和FICB可作为Stoppa方法髋臼骨折手术镇痛的有效途径。临床试验注册。该研究于2021年2月17日在临床试验注册系统前瞻性注册，注册号：IRCT20191114045435N1。