Purpose

Life review interventions aim to support individuals facing an incurable disease accompanied by existential concerns and health-related challenges. Based on encouraging feasibility results, this study assessed the effects of Revie ⊕ life review intervention on the self-esteem of patients with advanced cancer, and the effects on well-being, post-traumatic growth, life satisfaction, symptom burden and interaction with nurses.

Method

The study consisted of a two-arm parallel-group, waitlist-controlled trial (WCT) in the oncology division of a Swiss-French University Hospital. Revie ⊕ was composed of nurse-led meeting with the patient to address and document significant life events using a strengths-focused approach and targeting the life project.

Results

Due to Covid-19 pandemic, adjustments were made regarding study duration and participant's allocation: Fifty-eight patients received Revie ⊕, 39 completed all the measurements. Self-esteem was high at baseline and maintained stability over time. The social well-being decreased in the intervention group before-after Revie ⊕ (−1.7 (3.9), p = 0.044) while emotional and functional well-being showed stability. The intensity of symptoms decreased in the intervention group before-after Revie ⊕: 4.9 (9.4), p = 0.020.

Conclusions

This study suggests that patients living with an advanced cancer and who received Revie ⊕ intervention may have maintained their self-esteem high over time. Observed results are promising, particularly considering the influence of the pandemic. Nevertheless, these findings do not allow us to draw definitive conclusions regarding the efficacy of the intervention on self-esteem. WCT seems not to be the appropriate design to highlight the added value of Revie ⊕ for this particularly vulnerable population.

Clinical trial registration number

NCT04254926.

中文翻译：

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回顾⊕：基于资源的生活回顾干预对晚期癌症患者的影响：候补对照试验

目的

生活回顾干预措施旨在支持面临不治之症、伴有生存问题和健康相关挑战的个人。基于令人鼓舞的可行性结果，本研究评估了Revie⊕生活回顾干预对晚期癌症患者自尊的影响，以及对幸福感、创伤后成长、生活满意度、症状负担和与护士互动的影响。

方法

该研究包括在瑞士-法国大学医院肿瘤科进行的一项双臂平行组、候补对照试验（WCT）。 Revie ⊕ 由护士主导的与患者的会议组成，使用以优势为中心的方法并针对生活项目来解决和记录重要的生活事件。

结果

由于 Covid-19 大流行，研究持续时间和参与者分配进行了调整：58 名患者接受了 Revie ⊕，39 名患者完成了所有测量。自尊在基线时很高，并且随着时间的推移保持稳定。干预组的社会幸福感在 Revie ⊕ 前后有所下降（−1.7 (3.9)，p = 0.044），而情绪和功能幸福感则表现出稳定。干预组前后症状强度有所下降Revie ⊕：4.9 (9.4)，p = 0.020。

结论

这项研究表明，接受 Revie ⊕ 干预的晚期癌症患者可能会随着时间的推移保持较高的自尊。观察到的结果是有希望的，特别是考虑到大流行的影响。然而，这些发现并不能让我们就自尊干预的有效性得出明确的结论。 WCT 似乎不是突出 Revie ⊕ 对这一特别弱势群体的附加价值的适当设计。

临床试验注册号

NCT04254926。