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A sustainable and green approach towards the utilization of biopolymers for effective wound dressing applications: A detailed review
Nano-Structures & Nano-Objects Pub Date : 2024-01-05 , DOI: 10.1016/j.nanoso.2023.101086
Deepak Verma , Manunya Okhawilai , Senthilkumar Nangan , Vijay Kumar Thakur , Sreeraj Gopi , Kanagaraj Kuppusamy , Mohit Sharma , Hiroshi Uyama

Millions of people worldwide are suffering and struggling to obtain the most effective wound care/treatment. In previous years, a steep rise in metabolic disorders such as diabetic wound ulcers has been noticed. The primary function of an effective wound dressing is to protect the wound bed from contamination and provide an accelerated healing environment. Biopolymers, a natural boon, can be used for distinct applications from food packaging, biomedicine, and biomedical applications. Natural and synthetic biopolymers have distinct advantages, such as biocompatibility, biodegradability, and environmental friendliness. Cellulose, chitosan, alginates, hyaluronic acid, collagen, etc., are natural biopolymers primarily used to develop wound dressings. Most common synthetic biopolymers such as PVA, PCL, and PLA are examples of how an individual biopolymer or its blends can be used to develop an effective wound dressing. Biopolymer properties for wound dressing applications can be improved by applying the concepts of nanotechnology, bioengineering, and drug delivery. These improvements may help meet the current and future wound care demands for tissue repair and restoration. The current review focuses on using natural and synthetic functionalized biopolymers for effective wound-dressing applications and exhibiting their antibacterial and antimicrobial properties.

中文翻译:

利用生物聚合物进行有效伤口敷料应用的可持续和绿色方法:详细审查

全世界有数百万人正在遭受痛苦并努力获得最有效的伤口护理/治疗。前几年,人们注意到糖尿病伤口溃疡等代谢性疾病急剧增加。有效伤口敷料的主要功能是保护伤口床免受污染并提供加速愈合的环境。生物聚合物是一种天然恩赐,可用于食品包装、生物医学和生物医学应用等不同的应用。天然和合成生物聚合物具有独特的优势,例如生物相容性、生物可降解性和环境友好性。纤维素、壳聚糖、藻酸盐、透明质酸、胶原蛋白等是天然生物聚合物,主要用于开发伤口敷料。最常见的合成生物聚合物(例如 PVA、PCL 和 PLA)是如何使用单个生物聚合物或其混合物来开发有效伤口敷料的示例。通过应用纳米技术、生物工程和药物输送的概念,可以改善伤口敷料应用的生物聚合物特性。这些改进可能有助于满足当前和未来组织修复和恢复的伤口护理需求。当前的审查重点是使用天然和合成的功能化生物聚合物进行有效的伤口敷料应用,并展示其抗菌和抗菌特性。
更新日期:2024-01-05
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