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Evaluation of organ dose using size-specific dose estimation (SSDE) and related cancer risk due to chest CT scan during the COVID-19 pandemic
Radiation and Environmental Biophysics ( IF 1.7 ) Pub Date : 2024-01-07 , DOI: 10.1007/s00411-023-01056-x
Mostafa Robatjazi , Mahdis Moayed , Hamid Reza Baghani , Mikaeil Molazadeh , Nematullah Shomoossi

This study aimed to estimate lung and breast doses for individual patients using the size-specific dose estimate (SSDE) method, as well as calculating effective doses, in patients who underwent chest CT scans during the COVID-19 pandemic. Cancer risk incidence was estimated using excess relative risk (ERR), excess absolute risk (EAR), and lifetime attributable risk (LAR) models from the Biological Effects of Ionizing Radiation Report VII (BEIR-VII). Data from about 570 patients who underwent CT scans for COVID-19 screening were utilized for this study. Using the header of the CT images in a Python script, SSDE and effective dose were calculated for each patient. The SSDE obtained by water equivalent effective diameter (wSSDE) was considered as lung and breast dose, and applied in organ-specific cancer risk estimation. The mean wSSDE value for females (13.3 mGy) was slightly higher than that for males (13.1 mGy), but the difference was not statistically significant (P value = 0.41). No significant differences were observed between males and females in terms of calculated EAR and ERR for lung cancer at 5 and 30 years after exposure (P value = 0.47, 0.46, respectively). Similarly, there was no significant difference in lung cancer LAR values between females and males (P value = 0.48). The results also indicated a decrease in LAR values for both lung and breast cancers with increasing exposure age. In accordance with the ALARA (as low as reasonably achievable) principle, it is important for medical staff and the general public to consider the benefits of CT imaging in detecting such infections. Additionally, imaging medical physicists and CT scan experts should optimize imaging protocols and strike a balance between image quality for detecting abnormalities and radiation dose, all while adhering to the ALARA principle.



中文翻译:

使用尺寸特定剂量估计 (SSDE) 评估器官剂量以及 COVID-19 大流行期间胸部 CT 扫描导致的相关癌症风险

本研究旨在使用尺寸特定剂量估计 (SSDE) 方法估计个体患者的肺部和乳房剂量,并计算在 COVID-19 大流行期间接受胸部 CT 扫描的患者的有效剂量。使用电离辐射生物效应报告 VII (BEIR-VII) 中的超额相对风险 (ERR)、超额绝对风险 (EAR) 和终生归因风险 (LAR) 模型估算癌症风险发生率。本研究使用了约 570 名接受 CT 扫描进行 COVID-19 筛查的患者的数据。使用 Python 脚本中的 CT 图像标题,计算每位患者的 SSDE 和有效剂量。通过水当量有效直径(wSSDE)获得的SSDE被认为是肺和乳腺剂量,并应用于器官特异性癌症风险评估。女性平均wSSDE值(13.3 mGy)略高于男性(13.1 mGy),但差异无统计学意义(P值=0.41)。暴露后 5 年和 30 年计算得出的肺癌 EAR 和 ERR 方面,男性和女性之间没有观察到显着差异(P值分别为 0.47、0.46)。同样,女性和男性肺癌LAR值也没有显着差异(P值=0.48)。结果还表明,随着暴露年龄的增加,肺癌和​​乳腺癌的 LAR 值均下降。根据 ALARA(尽可能低)原则,医务人员和公众必须考虑 CT 成像在检测此类感染方面的益处。此外,成像医学物理学家和 CT 扫描专家应优化成像协议,并在检测异常的图像质量和辐射剂量之间取得平衡,同时遵守 ALARA 原则。

更新日期:2024-01-08
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