Objectives The aim of this study was to evaluate and characterize different methods to achieve interfragmentary compression during tibial plateau levelling osteotomy (TPLO).

Study Design TPLO was performed in 20 canine tibia models (Sawbones, Vashon, Washington, United States) using 3D-printed guides for standardization. Interfragmentary compression was assessed using pressure-sensitive films (Prescale, Fujifilm, Atherstone, United Kingdom). Seven compression methods were tested: (1) Kern bone holding forceps clamping the craniodistal aspect of the TPLO plate to the caudal aspect of the tibia (K); (2) using the distal TPLO plate dynamic compression hole (P); (3) pointed bone reduction forceps engaging the caudal aspect of the proximal bone fragment and the cranial aspect of the tibial crest (F); (4) K + P; (5) K + F; (6) F + P; and (7) K + F + P. Five measurements were obtained for each method, and each bone model was used for two measurements (single method, ± plate). The interfragmentary surface was digitalized and divided into quadrants for standardization and pixel density calculation: Q1, craniomedial; Q2, craniolateral; Q3, caudomedial; and Q4, caudolateral. One-way analysis of variance (ANOVA) and post hoc tests were used for statistical analysis.

Results Mean pressures per quadrant differed significantly between methods (p < 0.001). Methods K, F, and P produced more craniomedial, craniolateral, and caudal compression, respectively. Method K resulted in loss of caudal compression (p < 0.001). Method F + P provided the most even distribution of high interfragmentary compression forces. The addition of method K to this construct (K + F + P) marginally increased cranial compression (p = 0.189 for Q1; p < 0.001 for Q2), but reduced compression caudally (p < 0.001).

Conclusion Method F + P provided more even interfragmentary compression. If method K were used, then combined use with method F + P would be recommended.

目的 本研究的目的是评估和描述在胫骨平台整平截骨术 (TPLO) 期间实现骨折块间压缩的不同方法。

研究设计 TPLO 使用 3D 打印标准化指南在 20 个犬类胫骨模型（Sawbones，Vashon，华盛顿州，美国）中进行。使用压敏胶片（Prescale、Fujifilm、Atherstone、英国）评估碎片间压缩。测试了七种压缩方法：（1）Kern持骨钳将TPLO板的颅远侧夹至胫骨尾侧（K）；(2)采用远端TPLO板动态加压孔(P)；(3)尖头骨复位钳接合近端骨碎片的尾侧和胫骨嵴的颅侧(F)；(4)K+P；(5)K+F；(6)F+P；(7)K+F+P。每种方法获得五次测量，每个骨模型用于两次测量（单一方法，±平板）。将碎片间表面数字化并分为象限以进行标准化和像素密度计算：Q1，颅内侧；Q2，颅外侧；Q3，尾内侧；和 Q4，尾外侧。使用单因素方差分析（ANOVA）和事后检验进行统计分析。

结果 每个象限的平均压力在方法之间存在显着差异 ( p  < 0.001)。方法 K、F 和 P 分别产生更多的颅内、颅侧和尾部压缩。方法 K 导致尾部压缩丧失（p  < 0.001）。方法 F + P 提供了最均匀的高碎片间压缩力分布。在此构造中添加方法 K (K + F + P) 略微增加了颅骨压缩（ Q1 的p  = 0.189； Q2 的p  < 0.001），但减少了尾部的压缩（p  < 0.001）。

结论 F + P 方法提供了更均匀的骨折间压缩。如果使用方法K，则建议与方法F+P结合使用。