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Exploration of the profiles of steroidal saponins from Rhizoma Paridis and their metabolites in rats by UPLC-Q-TOF-MS/MS
Phytochemical Analysis ( IF 3.3 ) Pub Date : 2024-01-08 , DOI: 10.1002/pca.3317
Dong‐Rong Wu 1 , Xiao‐Wen Yang 1 , Qian Zhao 1 , Li‐Xia Wang 1 , Kai Guo 1 , Xiao Ye 1 , Xue‐Mei Niu 1, 2 , Sheng‐Hong Li 1 , Yan Liu 1
Affiliation  

Steroidal saponins characterised by intricate chemical structures are the main active components of a well-known traditional Chinese medicine (TCM) Rhizoma Paridis. The metabolic profiles of steroidal saponins in vivo remain largely unexplored, despite their renowned antitumor, immunostimulating, and haemostatic activity.

中文翻译:

UPLC-Q-TOF-MS/MS 探索重楼甾体皂苷及其在大鼠体内的代谢物谱

甾体皂苷具有复杂的化学结构,是著名中药重楼的主要活性成分。尽管甾体皂苷具有著名的抗肿瘤、免疫刺激和止血活性,但其体内代谢特征在很大程度上仍未被探索。
更新日期:2024-01-09
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