This systematic review summarizes the evidence on associations between physical and psychosocial work-related exposures and the development of carpal tunnel syndrome (CTS). Relevant databases were searched up to January 2020 for cohort studies reporting associations between work-related physical or psychosocial risk factors and the incidence of CTS. Two independent reviewers selected eligible studies, extracted relevant data, and assessed risk of bias (RoB). We identified fourteen articles for inclusion which reported data from nine cohort studies. Eight reported associations between physical exposure and the incidence of CTS and five reported associations between psychosocial exposures and the incidence of CTS. Quality items were generally rated as unclear or low RoB. Work-related physical exposure factors including high levels of repetition, velocity, and a combination of multiple physical exposures were associated with an increased risk of developing CTS. No other consistent associations were observed for physical or psychosocial exposures at work and CTS incidence.

本系统综述总结了与工作相关的身体和心理社会暴露与腕管综合症（CTS）发展之间关联的证据。截至 2020 年 1 月，我们检索了相关数据库，寻找报告与工作相关的身体或心理社会风险因素与 CTS 发病率之间关联的队列研究。两名独立评审员选择了符合条件的研究，提取相关数据并评估偏倚风险（RoB）。我们确定了十四篇文章纳入其中，其中报告了九项队列研究的数据。八项报道了身体暴露与 CTS 发病率之间的关联，五项报道了心理社会暴露与 CTS 发病率之间的关联。质量项目通常被评为不明确或低 RoB。与工作相关的身体暴露因素，包括高水平的重复、速度和多种身体暴露的组合，与发生 CTS 的风险增加相关。没有观察到工作中的身体或心理社会暴露与 CTS 发生率之间存在其他一致的关联。