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Artificial intelligence predicts direct-acting antivirals failure among hepatitis C virus patients: A nationwide hepatitis C virus registry program.
Clinical and Molecular Hepatology ( IF 8.9 ) Pub Date : 2023-11-21 , DOI: 10.3350/cmh.2023.0287 Ming-Ying Lu , Chung-Feng Huang , Chao-Hung Hung , Chi‐Ming Tai , Lein-Ray Mo , Hsing-Tao Kuo , Kuo-Chih Tseng , Ching-Chu Lo , Ming-Jong Bair , Szu-Jen Wang , Jee-Fu Huang , Ming-Lun Yeh , Chun-Ting Chen , Ming-Chang Tsai , Chien-Wei Huang , Pei-Lun Lee , Tzeng-Hue Yang , Yi-Hsiang Huang , Lee-Won Chong , Chien-Lin Chen , Chi-Chieh Yang , Sheng‐Shun Yang , Pin-Nan Cheng , Tsai-Yuan Hsieh , Jui-Ting Hu , Wen-Chih Wu , Chien-Yu Cheng , Guei-Ying Chen , Guo-Xiong Zhou , Wei-Lun Tsai , Chien-Neng Kao , Chih-Lang Lin , Chia-Chi Wang , Ta-Ya Lin , Chih‐Lin Lin , Wei-Wen Su , Tzong-Hsi Lee , Te-Sheng Chang , Chun-Jen Liu , Chia-Yen Dai , Jia-Horng Kao , Han-Chieh Lin , Wan-Long Chuang , Cheng-Yuan Peng , Chun-Wei- Tsai , Chi-Yi Chen , Ming-Lung Yu ,
Clinical and Molecular Hepatology ( IF 8.9 ) Pub Date : 2023-11-21 , DOI: 10.3350/cmh.2023.0287 Ming-Ying Lu , Chung-Feng Huang , Chao-Hung Hung , Chi‐Ming Tai , Lein-Ray Mo , Hsing-Tao Kuo , Kuo-Chih Tseng , Ching-Chu Lo , Ming-Jong Bair , Szu-Jen Wang , Jee-Fu Huang , Ming-Lun Yeh , Chun-Ting Chen , Ming-Chang Tsai , Chien-Wei Huang , Pei-Lun Lee , Tzeng-Hue Yang , Yi-Hsiang Huang , Lee-Won Chong , Chien-Lin Chen , Chi-Chieh Yang , Sheng‐Shun Yang , Pin-Nan Cheng , Tsai-Yuan Hsieh , Jui-Ting Hu , Wen-Chih Wu , Chien-Yu Cheng , Guei-Ying Chen , Guo-Xiong Zhou , Wei-Lun Tsai , Chien-Neng Kao , Chih-Lang Lin , Chia-Chi Wang , Ta-Ya Lin , Chih‐Lin Lin , Wei-Wen Su , Tzong-Hsi Lee , Te-Sheng Chang , Chun-Jen Liu , Chia-Yen Dai , Jia-Horng Kao , Han-Chieh Lin , Wan-Long Chuang , Cheng-Yuan Peng , Chun-Wei- Tsai , Chi-Yi Chen , Ming-Lung Yu ,
Despite the high efficacy of direct-acting antivirals (DAAs), approximately 1-3% of hepatitis C virus (HCV) patients fail to achieve a sustained virological response. We conducted a nationwide study to investigate risk factors associated with DAA treatment failure. Machine-learning algorithms have been applied to discriminate subjects who may fail to respond to DAA therapy.
中文翻译：
人工智能预测丙型肝炎病毒患者的直接抗病毒药物失败：全国丙型肝炎病毒登记计划。
尽管直接作用抗病毒药物 (DAA) 疗效很高，但约 1-3% 的丙型肝炎病毒 (HCV) 患者未能实现持续的病毒学应答。我们进行了一项全国性研究来调查与 DAA 治疗失败相关的风险因素。机器学习算法已被应用于区分可能对 DAA 治疗没有反应的受试者。
更新日期：2023-11-21
中文翻译：
人工智能预测丙型肝炎病毒患者的直接抗病毒药物失败：全国丙型肝炎病毒登记计划。
尽管直接作用抗病毒药物 (DAA) 疗效很高，但约 1-3% 的丙型肝炎病毒 (HCV) 患者未能实现持续的病毒学应答。我们进行了一项全国性研究来调查与 DAA 治疗失败相关的风险因素。机器学习算法已被应用于区分可能对 DAA 治疗没有反应的受试者。
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