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A Brief Review on Schiff Base, Synthesis, and Their Antimicrobial Activities
Russian Journal of Bioorganic Chemistry ( IF 1 ) Pub Date : 2024-01-10 , DOI: 10.1134/s1068162023080046
Ruaa M. Dhedan , Sanaa A. Alsahib , Rana Abid Ali

Abstract

The Schiff base chemsitry includes compounds that attracted the attention of research scope from the early years. Consequently, the Schiff base constitutes a significant source of compounds for new pharmacological developments. Several Schiff bases, including derivatives, were synthesized and assessed for biological activities they possess, containing antimicrobial, antioxidant, anti-inflammatory, anti-tuberculosis, anticonvulsants, anxiolytics, antidepressant, anticancer, antihypertensive,and anti-fungal activity. The Schiff Base research, including composites with a lower-side effect, and extra specific activity and remains a dynamic zone of debate in medicinal chemistry. The current wrok elaborately discusses the medicinal chemistry and its bio-logical qualities.



中文翻译:

希夫碱、合成及其抗菌活性简述

摘要

希夫碱化学包括早年引起研究领域关注的化合物。因此,希夫碱构成了新药理学开发的重要化合物来源。合成了几种希夫碱,包括衍生物,并评估了它们所具有的生物活性,包括抗菌、抗氧化、抗炎、抗结核、抗惊厥、抗焦虑、抗抑郁、抗癌、抗高血压和抗真菌活性。希夫碱研究,包括具有较低副作用和更高比活性的复合材料,仍然是药物化学领域争论的一个动态领域。当前的工作详细讨论了药物化学及其生物特性。

更新日期:2024-01-10
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