Abstract

Heterogeneous catalysts have been widely used in recent research because of their several advantages such as selectivity, minimization of waste product, low cost, easy separation from reaction mixture, and toleration of a wide range of temperatures and pressures. On the other hand, due to the presence of aldehydes and ketones in many target molecules such as drugs and natural products, oxidation of alcohols to the corresponding carbonyl compounds is one of the most common fundamental transformations in both laboratory and industrial synthetic chemistry. Therefore, in this study an impressive catalytic method has been presented for the synthesis of ketones and aldehydes via oxidation of alcohols with hydrogen peroxide in aqueous acetonitrile in the presence of Cs₃NaV₄O₁₂(H₂O) heteropolyacid as catalyst. One of the advantages of this catalyst is the ability to be reused in at least four consecutive reactions without significant loss of activity, in addition to seriously shortening the oxidation time compared to some previously reported methods.

中文翻译：

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Cs3NaV4O12(H2O)杂多酸的制备及其在有机化合物氧化中的应用

摘要

多相催化剂因其选择性、废物最少化、成本低、易于从反应混合物中分离以及耐受较宽的温度和压力范围等优点而在最近的研究中得到广泛应用。另一方面，由于药物和天然产物等许多目标分子中存在醛和酮，醇氧化成相应的羰基化合物是实验室和工业合成化学中最常见的基本转化之一。_{因此，在这项研究中，提出了一种令人印象深刻的催化方法，在 Cs 3} NaV ₄ O ₁₂ (H ₂ O)杂多酸作为催化剂的存在下，通过在乙腈水溶液中用过氧化氢氧化醇来合成酮和醛。这种催化剂的优点之一是能够在至少四个连续反应中重复使用而不会显着损失活性，此外与之前报道的一些方法相比还大大缩短了氧化时间。