Abstract

The review briefly describes the synthetic potential of acetylenic and allenic carbanion adducts with isothiocyanates and azatriene systems based thereon as precursors to fundamental aza- and thiaheterocycles, namely pyrroles, 2,3-dihydropyridines, pyridines, quinolines, 3H-azepines, 4,5-dihydro-3H-azepines, 2-azabi­cyclo[3.2.0]hept-2-enes, thietanes, thiophenes, thiophen-2(5H)-imines, 1,3-thiazoles, 4,5-dihydro-1,3-thiazoles, and other heterocyclic structures with rare and/or difficultly introducible functional and pharmacophoric substituents.

中文翻译：

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乙炔和烯丙碳负离子与杂积烯的反应：获得基本杂环的直接途径

摘要

该综述简要描述了乙炔和丙二烯碳负离子加合物与异硫氰酸酯和基于其的氮杂三烯系统作为基本氮杂环和硫杂环前体的合成潜力，即吡咯、2,3-二氢吡啶、吡啶、喹啉、3 H-氮杂环庚烷、4,5 -二氢-3 H -氮杂平、2-氮杂双环[3.2.0]庚-2-烯、硫杂环丁烷、噻吩、噻吩-2(5 H )-亚胺、1,3-噻唑、4,5-二氢-1、 3-噻唑和其他具有罕见和/或难以引入的功能和药效取代基的杂环结构。