Objectives

The Caregiver’s Inventory Neuropsychological Diagnosis Dementia (CINDD) is an easy tool designed to quantify cognitive, behavioural and functional deficits of patients with cognitive impairment. Aim of the present study was to analyse the psychometric properties of the CINDD in Mild Cognitive Impairment (MCI) and Dementia (D).

Design, setting and participants

The CINDD, composed by 9 sub-domains, was administered to fifty-six caregivers of patients with different types of dementia (D) and 44 caregivers of patients with MCI. All patients underwent an extensive neuropsychological assessment, the Neuropsychiatric Inventory (NPI) and functional autonomy scales. The reliability, convergent construct validity and possible cut-off of CINND were measured by Cronbach’s alpha (α), Pearson’s correlation and ROC analysis, respectively.

Results

The D and MCI patients differed only for age (p=0.006). The internal consistency of CINDD was high (α= 0.969). The α-value for each CINDD domain was considered acceptable, except the mood domain (α=0.209). The CINDD total score correlated with cognitive screening tests; each domain of the CINDD correlated with the corresponding score from either tests or NPI (p<0.05), except for visuo-spatial perception skills and apathy. A screening cut-off equal to 59, can be used discriminate D from MCI (Sensitivity=0.70, Specificity=0.57).

Conclusion

The CINDD is a feasible, accurate and reliable tool for the assessment of cognitive and behavioural difficulties in patients with different degree of cognitive impairment. It may be used to quantify and monitor caregiver-reported ecological data in both clinical and research settings.

中文翻译：

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轻度认知障碍和痴呆中看护者神经心理学诊断痴呆 (CINDD) 的心理测量特性

目标

护理人员痴呆症神经心理学诊断清单 (CINDD) 是一种简单的工具，旨在量化认知障碍患者的认知、行为和功能缺陷。本研究的目的是分析 CINDD 在轻度认知障碍 (MCI) 和痴呆 (D) 中的心理测量特性。

设计、设置和参与者

CINDD 由 9 个子域组成，对 56 名不同类型痴呆 (D) 患者的护理人员和 44 名 MCI 患者的护理人员进行了研究。所有患者均接受了广泛的神经心理学评估、神经精神量表（NPI）和功能自主量表。CINND 的信度、收敛结构效度和可能的截止值分别通过 Cronbach's alpha (α)、Pearson 相关性和 ROC 分析来测量。

结果

D 型和 MCI 患者仅在年龄上存在差异 (p=0.006)。CINDD的内部一致性较高（α=0.969）。每个 CINDD 域的 α 值被认为是可接受的，除了情绪域 (α=0.209)。CINDD 总分与认知筛查测试相关；CINDD 的每个领域都与测试或 NPI 的相应分数相关（p<0.05），但视觉空间感知技能和冷漠除外。筛选截止值等于 59，可用于区分 D 与 MCI（灵敏度=0.70，特异性=0.57）。

结论

CINDD是评估不同程度认知障碍患者认知和行为困难的可行、准确、可靠的工具。它可用于量化和监测临床和研究环境中护理人员报告的生态数据。