Purpose

We assessed the association between oral frailty risk and LUTS among middle-aged and older adults in a community-dwelling population.

Methods

This cross-sectional study was conducted among 586 subjects aged ≥ 40 years who participated in the Iwaki Health Promotion Project in Hirosaki, Japan. We used the International Prostate Symptom Score (IPSS) and the Overactive Bladder Symptom Score (OABSS) to assess LUTS. LUTS was defined as an IPSS score of 8 or higher or meeting diagnostic criteria for OAB. Oral frailty risk was defined as experiencing two or more of the following: decreased chewing ability, decreased biting force, and dry mouth sensation. Physical performance (10-m gait speed and grip strength) was used for analysis. The association between oral frailty risk and LUTS was examined using multivariate logistic regression analyses.

Results

The study included 218 men and 370 women, of whom 140 had LUTS. The mean age of this cohort was 59 years. Significant differences were observed between the LUTS and non-LUTS groups, including age, hypertension, history of CVD, depressive status, sleep disturbance, and 10 m gait speed. The prevalence of oral frailty risk was significantly higher in the LUTS group than in the non-LUTS group (26% vs. 11%, P < 0.001). Multivariate analysis revealed that age, male gender, and oral frailty risk (odds ratio: 2.67, 95% confidence interval: 1.57–4.51, P < 0.001) were independent factors for LUTS. Moreover, oral frailty risk was an independent factor in both participants aged < 65 years and participants aged ≥ 65 years.

Conclusions

Oral frailty was independently associated with LUTS.

中文翻译：

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社区居民中老年人口腔脆弱与下尿路症状之间的关联：一项横断面研究

目的

我们评估了社区居住人群中老年人口腔衰弱风险与 LUTS 之间的关联。

方法

这项横断面研究是在参加日本弘前市磐城健康促进项目的 586 名年龄 ≥ 40 岁的受试者中进行的。我们使用国际前列腺症状评分 (IPSS) 和膀胱过度活动症状评分 (OABSS) 来评估 LUTS。LUTS 被定义为 IPSS 得分为 8 或更高或符合 OAB 的诊断标准。口腔脆弱风险被定义为出现以下两种或多种情况：咀嚼能力下降、咬合力下降和口干感。物理性能（10 米步态速度和握力）用于分析。使用多变量逻辑回归分析检查口腔衰弱风险与 LUTS 之间的关联。

结果

该研究包括 218 名男性和 370 名女性，其中 140 人患有 LUTS。该队列的平均年龄为 59 岁。LUTS 组和非 LUTS 组之间观察到显着差异，包括年龄、高血压、CVD 病史、抑郁状态、睡眠障碍和 10 m 步速。LUTS 组口腔衰弱风险的发生率显着高于非 LUTS 组（26% vs. 11%，P < 0.001）。多变量分析显示，年龄、男性和口腔脆弱风险（比值比：2.67，95% 置信区间：1.57–4.51，P < 0.001）是 LUTS 的独立因素。此外，口腔衰弱风险对于年龄 < 65 岁的参与者和年龄 ≥ 65 岁的参与者来说都是一个独立因素。

结论

口腔脆弱与 LUTS 独立相关。