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Prediction of combination effect of quinidine on the pharmacokinetics of tipepidine using a physiologically based pharmacokinetic model
Xenobiotica ( IF 1.8 ) Pub Date : 2024-01-17 , DOI: 10.1080/00498254.2024.2304129 Shun Hayashi 1, 2 , Hiroko Kawaguchi 1 , Takao Watanabe 3 , Izuru Miyawaki 1 , Tatsuki Fukami 2, 4 , Miki Nakajima 2, 4
Xenobiotica ( IF 1.8 ) Pub Date : 2024-01-17 , DOI: 10.1080/00498254.2024.2304129 Shun Hayashi 1, 2 , Hiroko Kawaguchi 1 , Takao Watanabe 3 , Izuru Miyawaki 1 , Tatsuki Fukami 2, 4 , Miki Nakajima 2, 4
Affiliation
Tipepidine, an antitussive drug, has been reported to have central pharmacological effects and can be expected to be safely repositioned as treatment for psychiatric disorders. Since tipepidine req...
中文翻译：
使用基于生理学的药代动力学模型预测奎尼丁对替哌啶药代动力学的联合效应
据报道，替哌啶是一种镇咳药物，具有重要的药理作用，有望被安全地重新定位为精神疾病的治疗方法。由于替培定需要...
更新日期：2024-01-17
中文翻译：
使用基于生理学的药代动力学模型预测奎尼丁对替哌啶药代动力学的联合效应
据报道，替哌啶是一种镇咳药物，具有重要的药理作用，有望被安全地重新定位为精神疾病的治疗方法。由于替培定需要...
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