Protease inhibitors (PIs) have been recommended as World Health Organization second-line antiretroviral therapy (ART) for low- to middle-income countries for two decades. As dolutegravir-based regimens have become widely available, the future role of PIs is uncertain.

中文翻译：

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三级抗逆转录病毒诊所使用蛋白酶抑制剂的患者的结果和特征。

二十年来，蛋白酶抑制剂（PI）一直被世界卫生组织推荐为中低收入国家的二线抗逆转录病毒疗法（ART）。随着基于多替拉韦的治疗方案已广泛应用，PI 的未来作用尚不确定。