Intramuscular injection of palmitic acid-conjugated Exendin-4 loaded multivesicular liposomes for long-acting and improving in-situ stability,Expert Opinion on Drug Delivery

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Intramuscular injection of palmitic acid-conjugated Exendin-4 loaded multivesicular liposomes for long-acting and improving in-situ stability
Expert Opinion on Drug Delivery ( IF 6.6 ) Pub Date : 2024-01-31 , DOI: 10.1080/17425247.2024.2305110
Huixian Tian ₁ , Minsi Chang ₁ , Yanlin Lyu ₁ , Nan Dong ₁ , Nini Yu ₁ , Tian Yin ₂ , Yu Zhang ₁ , Haibing He ₁ , Jingxin Gou ₁ , Xing Tang ₁

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Exendin-4 (Ex4) is a promising drug for diabetes mellitus with a half-life of 2.4 h in human bodies. Besides, the Ex4 formulations currently employed in the clinic or under development have problem...

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