Identification and evaluation of antiviral activity of novel compounds targeting SARS-CoV-2 virus by enzymatic and antiviral assays, and computational analysis,Journal of Enzyme inhibition and Medicinal Chemistry

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Identification and evaluation of antiviral activity of novel compounds targeting SARS-CoV-2 virus by enzymatic and antiviral assays, and computational analysis
Journal of Enzyme inhibition and Medicinal Chemistry ( IF 5.6 ) Pub Date : 2024-01-14 , DOI: 10.1080/14756366.2024.2301772
Ivana Nemčovičová ₁ , Katarína Lopušná ₁ , Iveta Štibrániová ₁ , Fabio Benedetti ₂ , Federico Berti ₂ , Fulvia Felluga ₂ , Sara Drioli ₂ , Mattia Vidali ₂ , Jaroslav Katrlík ₃ , Lucia Pažitná ₃ , Alena Holazová ₃ , Jana Blahutová ₃ , Simona Lenhartová ₁ , Monika Sláviková ₁ , Boris Klempa ₁ , Miroslav Ondrejovič _{4,

5} , Daniela Chmelová ₄ , Barbora Legerská ₄ , Stanislav Miertuš _{4,

5} , Mária Klacsová ₆ , Daniela Uhríková ₆ , Lukáš Kerti ₆ , Vladimír Frecer ₆

Affiliation

The viral genome of the SARS-CoV-2 coronavirus, the aetiologic agent of COVID-19, encodes structural, non-structural, and accessory proteins. Most of these components undergo rapid genetic variatio...

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