Patients with scoliosis present gait impairments compared to healthy subjects. Clinically, spine deformity is evaluated with Cobb angle, a standard measurement to determine and track the progression of scoliosis. Scoliosis is a biomechanical trouble, dependant of external forces and muscular activity. External work is currently analyzed in patients with scoliosis because this work sums up consequences and evolutions of spine deformity. Habitually, biomechanics approach is used to compute this work. For asymptomatic subjects, a regression model let to compute external work. So, considering the area of research to facilitate the follow-up at lower cost, this regression function could be applied to patients with scoliosis but need to be validated. Research question: can external work during walking in scoliosis patients be estimated from spatiotemporal parameters with a regression model? This retrospective study included twenty untreated patients with idiopathic scoliosis and sixteen asymptomatic participants. We used a regression model defined in case of asymptomatic subjects in literature and proposed a new specific model in case of patients with scoliosis. The external work in patients with scoliosis calculated with the Wirta's regression eq. (0.23 ± 0.04 J.kg.m) was underestimated compared to the external work calculated using a biomechanical method (0.33 ± 0.06 J.kg.m). A new regression model including Cobb angle and spatio-temporal parameter presents a high coefficient of determination. In opposition to biomechanical method, our new model let to compute external work without expensive gait laboratory. This specific model is more reliable than the model developed from asymptomatic subjects.

中文翻译：

---

可以根据时空参数估计脊柱侧凸患者行走期间的外部工作吗？

与健康受试者相比，脊柱侧弯患者存在步态障碍。临床上，脊柱畸形通过科布角进行评估，科布角是确定和跟踪脊柱侧凸进展的标准测量方法。脊柱侧凸是一种生物力学问题，依赖于外力和肌肉活动。目前正在分析脊柱侧凸患者的外部工作，因为这项工作总结了脊柱畸形的后果和演变。通常，使用生物力学方法来计算这项工作。对于无症状受试者，回归模型可以计算外部功。因此，考虑到以较低成本促进随访的研究领域，该回归函数可以应用于脊柱侧凸患者，但需要验证。研究问题：可以通过回归模型从时空参数估计脊柱侧凸患者行走期间的外部工作吗？这项回顾性研究包括 20 名未经治疗的特发性脊柱侧凸患者和 16 名无症状参与者。我们使用了文献中针对无症状受试者定义的回归模型，并针对脊柱侧凸患者提出了一种新的特定模型。使用 Wirta 回归方程计算脊柱侧弯患者的外部功。与使用生物力学方法计算的外部功 (0.33 ± 0.06 J.kg.m) 相比，(0.23 ± 0.04 J.kg.m) 被低估。包含科布角和时空参数的新回归模型具有较高的决定系数。与生物力学方法相反，我们的新模型无需昂贵的步态实验室即可计算外部功。这个特定模型比无症状受试者开发的模型更可靠。