Design, synthesis, and bioevaluation of 1h-pyrrolo[3,2-c]pyridine derivatives as colchicine-binding site inhibitors with potent anticancer activities,Journal of Enzyme inhibition and Medicinal Chemistry

当前位置： X-MOL 学术 › J. Enzyme Inhib. Med. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Design, synthesis, and bioevaluation of 1h-pyrrolo[3,2-c]pyridine derivatives as colchicine-binding site inhibitors with potent anticancer activities
Journal of Enzyme inhibition and Medicinal Chemistry ( IF 5.6 ) Pub Date : 2024-01-14 , DOI: 10.1080/14756366.2024.2302320
Chao Wang _{1,

2} , Yujing Zhang ₃ , Shanbo Yang _{1,

2} , Lingyu Shi _{1,

2} , Rong Rong ₄ , Tingting Zhang _{1,

2} , Yudong Wu _{1,

2} , Dongming Xing _{1,

2,

5}

Affiliation

A new series of 1H-pyrrolo[3,2-c]pyridine derivatives were designed and synthesised as colchicine-binding site inhibitors. Preliminary biological evaluations showed that most of the target compound...

中文翻译：