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Rationality of the ethanol precipitation process in modern preparation production of Zishui-Qinggan decoction evaluated by integrating UPLC-QTOF-MS/MS-based chemical profiling/serum pharmacochemistry and network pharmacology
Phytochemical Analysis ( IF 3.3 ) Pub Date : 2024-01-14 , DOI: 10.1002/pca.3325 Cheng‐Ying Wu 1, 2 , Yi‐Yin Guo 1 , Zhen‐Yue Ma 1 , Jing Zhou 2 , Fang Long 1 , Hong Shen 2 , Jin‐Di Xu 1 , Shan‐Shan Zhou 2 , Jie‐Ge Huo 3 , Can‐Hong Hu 3 , Song‐Lin Li 1, 2
Phytochemical Analysis ( IF 3.3 ) Pub Date : 2024-01-14 , DOI: 10.1002/pca.3325 Cheng‐Ying Wu 1, 2 , Yi‐Yin Guo 1 , Zhen‐Yue Ma 1 , Jing Zhou 2 , Fang Long 1 , Hong Shen 2 , Jin‐Di Xu 1 , Shan‐Shan Zhou 2 , Jie‐Ge Huo 3 , Can‐Hong Hu 3 , Song‐Lin Li 1, 2
Affiliation
Zishui-Qinggan decoction (ZQD) is a classical traditional Chinese medicine formula (TCMF) for alleviating menopausal symptoms (MPS) induced by endocrine therapy in breast cancer patients. In the production of TCMF modern preparations, ethanol precipitation (EP) is a commonly but not fully verified refining process.
中文翻译:
基于UPLC-QTOF-MS/MS的化学分析/血清药物化学和网络药理学相结合评价紫水清感汤现代制剂生产中乙醇沉淀工艺的合理性
紫水清肝汤(ZQD)是一种经典中药方剂(TCMF),用于缓解乳腺癌患者内分泌治疗引起的更年期症状(MPS)。在TCMF现代制剂的生产中,乙醇沉淀(EP)是一种常见但尚未完全验证的精炼工艺。
更新日期:2024-01-16
中文翻译:
基于UPLC-QTOF-MS/MS的化学分析/血清药物化学和网络药理学相结合评价紫水清感汤现代制剂生产中乙醇沉淀工艺的合理性
紫水清肝汤(ZQD)是一种经典中药方剂(TCMF),用于缓解乳腺癌患者内分泌治疗引起的更年期症状(MPS)。在TCMF现代制剂的生产中,乙醇沉淀(EP)是一种常见但尚未完全验证的精炼工艺。