The oxidative cleavage reaction of pyrrolidine-2-methanols to γ-lactams has been described. In this reaction, [4-iodo-3-(isopropylcarbamoyl)phenoxy]acetic acid and powdered Oxone (2KHSO₅·KHSO₄·K₂SO₄) were employed as the catalyst and co-oxidant, respectively. The reaction is efficient and environmentally benign because it produces various lactams from readily available substrates in moderate to excellent yields using organocatalyst and inorganic non-toxic co-oxidant.

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中文翻译：

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使用 2-碘苯甲酰胺作为催化剂和 Oxone 将吡咯烷-2-甲醇高效且环保地氧化裂解为 γ-内酰胺

吡咯烷-2-甲醇氧化裂解成γ-内酰胺的反应已被描述。在该反应中，[4-碘-3-(异丙基氨基甲酰基)苯氧基]乙酸和粉末Oxone (2KHSO ₅ ·KHSO ₄ ·K ₂ SO ₄ )分别用作催化剂和助氧化剂。该反应高效且环境友好，因为它使用有机催化剂和无机无毒助氧化剂从容易获得的底物中以中等至优异的产率生产各种内酰胺。

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