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Salt sensitivity risk derived from nocturnal dipping and 24-h heart rate predicts long-term blood pressure reduction following renal denervation.
Journal of Hypertension ( IF 4.9 ) Pub Date : 2024-01-11 , DOI: 10.1097/hjh.0000000000003655
Gianni Sesa-Ashton 1, 2 , Revathy Carnagarin 3 , Janis M. Nolde 3 , Ida Muente 3 , Rebecca Lee 1 , Vaughan G. Macefield 2 , Tye Dawood 2 , Yusuke Sata 1, 4 , Elisabeth A. Lambert 5 , Gavin W. Lambert 5 , Antony Walton 4 , Marcio G. Kiuchi 3 , Murray D. Esler 1, 4 , Markus P. Schlaich 1, 3, 6
Affiliation  

Renal denervation (RDN) has been consistently shown in recent sham-controlled clinical trials to reduce blood pressure (BP). Salt sensitivity is a critical factor in hypertension pathogenesis, but cumbersome to assess by gold-standard methodology. Twenty-four-hour average heart rate (HR) and mean arterial pressure (MAP) dipping, taken by ambulatory blood pressure monitoring (ABPM), stratifies patients into high, moderate, and low salt sensitivity index (SSI) risk categories.

中文翻译:

夜间浸渍和 24 小时心率产生的盐敏感性风险可预测肾去神经支配后的长期血压降低。

最近的假手术对照临床试验一致表明去肾神经术(RDN)可以降低血压(BP)。盐敏感性是高血压发病机制的关键因素,但通过金标准方法进行评估很麻烦。通过动态血压监测 (ABPM) 获取的 24 小时平均心率 (HR) 和平均动脉压 (MAP) 下降,将患者分为高、中和低盐敏感性指数 (SSI) 风险类别。
更新日期:2024-01-11
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