In women of reproductive age, endometriosis may contribute to dysmenorrhea, chronic pelvic pain, dyspareunia, infertility, adenomyosis, and endometrial ovarian cyst (EOC). Recent studies have shown that chronic inflammation occurs in the pelvis of endometriosis patients and that this inflammation is exacerbated by immunosuppression, leading to survival endometrial debris. However, the detailed immunological mechanisms underlying the aggravation of inflammation and immunosuppression in endometriosis patients remain unclear.

中文翻译：

---

巨噬细胞模式识别受体的下调参与子宫内膜异位症的恶化

在育龄妇女中，子宫内膜异位症可能导致痛经、慢性盆腔疼痛、性交困难、不孕、子宫腺肌症和子宫内膜卵巢囊肿 (EOC)。最近的研究表明，子宫内膜异位症患者的骨盆会发生慢性炎症，并且免疫抑制会加剧这种炎症，导致子宫内膜碎片存活。然而，子宫内膜异位症患者炎症加重和免疫抑制的详细免疫学机制仍不清楚。