Pancreatic ductal adenocarcinoma (PDAC) has a fibrotic stroma that has both tumor-promoting and tumor-restraining properties. Different types of cancer-associated fibroblasts (CAFs) have been described. Here, we investigated whether CAFs within the same subtype exhibit heterogeneous functions.

中文翻译：

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胰腺癌中肌纤维母细胞癌相关成纤维细胞亚型异质性

胰腺导管腺癌 (PDAC) 的纤维化基质具有促肿瘤和抑制肿瘤的特性。不同类型的癌症相关成纤维细胞 (CAF) 已被描述。在这里，我们研究了同一亚型内的 CAF 是否表现出异质功能。